Neuroscience

Neuroscience (nature.com):
The NMDAR/TRPM4 death complex is a major promoter of disease progression in the 5xFAD mouse model of Alzheimer’s disease
Neuroscience (qbi.uq.edu.au):
Researchers have discovered a critical link between the brain’s waste-clearing system and early neuron degeneration in Alzheimer’s disease. The study shows that the first neurons to die in Alzheimer’s also regulate fluid flow essential for clearing brain toxins.
Neuroscience (qbi.uq.edu.au):
Unlocking the nanoscale—a new era in protein tracking
Neuroscience (psypost.org):
Evolution may have capped human brain size to balance energy costs and survival
Neuroscience (doaj.org):
Altered Visual Attention at 12 Months Predicts Joint Attention Ability and Socio-Communicative Development at 24 Months: A Single-Center Eye-Tracking Study on Infants at Elevated Likelihood to Develop Autism
Neuroscience (sciencedirect.com):
Glutamate excitotoxicity in dopaminergic neurons is strongly implicated in Parkinson’s disease. A new review outlines early overactivity and later reductions in signaling.
Neuroscience (massgeneralbrigham.org):
Researchers Find Link Between History of Traumatic Brain Injury and Development of Malignant Brain Tumor
Neuroscience (sciencedirect.com):
In rats, early-life stress via maternal separation induces widespread DNA methylation changes in prefrontal cortex, enriching glutamatergic, MAPK, and calcium channel pathways
Neuroscience (nature.com):
A new study in mice shows that while brief food smells spark hunger, prolonged exposure makes them eat less. Brain circuits linking smell and appetite explain this effect.
Neuroscience (mdpi.com):
Glutamate is implicated in migraine pathophysiology. NMDA, AMPA, and kainate antagonists, plus approaches that target metabotropic glutamate receptors (mGlu), are evaluated for potential to reduce attacks and symptoms.